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How Semaglutide works
Semaglutide works by mimicking a natural hormone in your body called GLP-1 (glucagon-like peptide 1), which plays a key role in regulating your appetite and blood sugar levels. When you take semaglutide, it helps your body feel fuller for longer, which can reduce hunger and make it easier to stick to healthier eating habits.
It also slows down the emptying of your stomach, which helps you feel satisfied after eating smaller amounts of food. By targeting both appetite and glucose control, semaglutide helps create a balanced environment in your body, supporting weight loss over time.
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How Tirzepatide works
Tirzepatide works similarly to semaglutide by mimicking your natural GLP-1 hormone, which helps regulate appetite and blood sugar. However, tirzepatide also targets another hormone, GIP (gastric inhibitory polypeptide) which further enhances its effect on appetite control and insulin sensitivity.
Like semaglutide, tirzepatide helps reduce hunger, increase feelings of fullness, and support weight loss when combined with a healthy lifestyle.
Both Semaglutide and Tirzepatide are powerful medications that have been shown to reduce weight when combined with healthy lifestyle changes like improved diet and regular exercise. This combination supports sustainable weight management and helps you make lasting progress toward your goals.
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GLP-1 is a hormone naturally produced in the intestines in response to food intake.
It plays a crucial role in regulating blood sugar levels and appetite. GLP-1 helps stimulate insulin release when blood sugar is high, slows down stomach emptying to promote fullness, and reduces hunger. These combined effects help with weight management and improve overall metabolic health.
The main difference is that Semaglutide only targets the GLP-1 hormone, while Tirzepatide targets both GLP-1 and GIP hormones.
This “dual action” makes Tirzepatide potentially more effective for weight loss and metabolism.
However, 70% of WeightCare members are actively losing or maintaining their weight with Semaglutide. The choice is yours!
Starting low and going slow with GLP-1 medication is key to a smoother experience. It helps your body adjust, reduces side effects, and sets the stage for steady, sustainable weight loss.
Both Semaglutide and Tirzepatide have been clinically shown to provide weight loss results for eligible patients.
Tirzepatide has shown greater weight reduction in head-to-head comparisons.
Semaglutide (2.4 mg, for weight loss): • ~15% body weight reduction.
Tirzepatide (15 mg): • ~20% body weight reduction.
Sources:
1. New England Journal of Medicine. Weight loss outcomes in the SURMOUNT-1 trial. 2022;387(3):205-216. doi:10.1056/NEJMoa2206038.2. (Tirzepatide)
2. U.S. Food and Drug Administration. FDA approves new drug treatment for chronic weight management, first since 2014. Published June 4, 2021. (Semaglutide)
Sustainable Weight Loss Made Possible
By mimicking hormones that regulate appetite and metabolism, GLP-1 medications empower you to achieve lasting results. With WeightCare’s supportive, nonjudgmental approach, you can confidently meet — and maintain — your health goals!
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